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Cheap Flights from Mexico City to Santiago starting at S$ 246

Book one-way or return flights from Mexico City to Santiago from as little as S$ 246. Choose from the popular airlines below and book your flight today!

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Searching for the best last minute flight from Mexico City to Santiago? Find one-way or return flights that are affordable and fit your itinerary.

Trip.com monitors the ticket fares of flights from Mexico City to Santiago. Stay updated on price trends and snag the best deals for your upcoming trip.

Displayed prices are calculated based on the lowest average weekly prices of the corresponding route on Trip.com.
Cheapest Airlines flying from Mexico City to Santiago

View airlines operating flights from Mexico City to Santiago. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Copa Airlines
From S$ 246
American Airlines
From S$ 429
Volaris
From S$ 465
Viva Aerobus
From S$ 491
Avianca
From S$ 504
Aeromexico
From S$ 517
United Airlines
From S$ 533
Air Canada
From S$ 651
Delta Air Lines
From S$ 744
ANA airlines

Find more flights and airlines

Alternative Routes from Mexico City to Santiago

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Mexico City to Santiago.

  • Cheapest
    Copa Airlines
    NLU
    14:37
    22h 23m
    1 transfer
    STI
    15:00
    Felipe Ángeles International Airport - Cibao International Airport
    Mon, Jun 3Copa Airlines
    S$ 246
  • American Airlines
    MEX
    05:25
    29h 0m
    1 transfer
    STI
    12:25
    Mexico City International Airport - Cibao International Airport
    Sun, Jun 2American Airlines
    S$ 429
  • American Airlines
    MEX
    05:25
    29h 0m
    1 transfer
    STI
    12:25
    Mexico City International Airport - Cibao International Airport
    Sun, Jun 2American Airlines
    S$ 429
    Find More Flights

Frequently Asked Questions

  • When to buy flight tickets from Mexico City (MEX) to Santiago (STI) the cheapest?

    Airlines adjust prices for flights from Mexico City to Santiago based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much is a flight from Mexico City (MEX) to Santiago (STI) cost?

    According to Trip.com's data, the lowest price is around S$ 1,014.
  • What is the transportation method from the main airport to downtown in Santiago?

    • The distance from Cibao International Airport to downtown is about 12km, by taxi about 30 minutes.
  • How many airports in Santiago?

    There are 1 airports near Santiago: Cibao International Airport.

How to find a cheap flight from Mexico City to Santiago

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Mexico City to Santiago. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com
Flight Information from Mexico City to Santiago

Cheapest direct flight price

S$ 246

Cheapest month

February

Peak season for travel

July

Flight distance

2,983.05km

Popular airline

American Airlines