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Cheap Flights from Panama City to Santa Cruz starting at S$ 212

Book one-way or return flights from Panama City to Santa Cruz from as little as S$ 212. Choose from the popular airlines below and book your flight today!

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Searching for the best last minute flight from Panama City to Santa Cruz? Find one-way or return flights that are affordable and fit your itinerary.

Trip.com monitors the ticket fares of flights from Panama City to Santa Cruz. Stay updated on price trends and snag the best deals for your upcoming trip.

Displayed prices are calculated based on the lowest average weekly prices of the corresponding route on Trip.com.
Cheapest Airlines flying from Panama City to Santa Cruz

View airlines operating flights from Panama City to Santa Cruz. Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Avianca
From S$ 212
Copa Airlines
From S$ 461
United Airlines
From S$ 805
American Airlines
From S$ 893
ANA airlines

Find more flights and airlines

Alternative Routes from Panama City to Santa Cruz

Discover different routes, airlines, and transfers and find the best alternative flights for your journey from Panama City to Santa Cruz.

  • Cheapest
    Avianca
    PTY
    17:40
    7h 20m
    1 transfer
    VVI
    02:00
    Tocumen International Airport - Viru Viru International Airport
    Wed, May 1Avianca
    S$ 212
  • Avianca
    PTY
    17:40
    7h 20m
    1 transfer
    VVI
    02:00
    Tocumen International Airport - Viru Viru International Airport
    Wed, May 1Avianca
    S$ 212
    Find More Flights

Frequently Asked Questions

  • When to buy flight tickets from Panama City (PTY) to Santa Cruz (SRZ) the cheapest?

    Airlines adjust prices for flights from Panama City to Santa Cruz based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much is a flight from Panama City (PTY) to Santa Cruz (SRZ) cost?

    According to Trip.com's data, the lowest price is around S$ 596.
  • How long is a flight from Panama City (PTY) to Santa Cruz (SRZ)?

    It takes about 5 hours to fly from Panama City (PTY) to Santa Cruz (SRZ).
  • What is the transportation method from the main airport to downtown in Santa Cruz?

    • The distance from Viru Viru International Airport to downtown is about 17km, by taxi about 30 minutes.
  • What time does the latest flight from Panama City to Santa Cruz depart?

    The latest flight departs from Panama City (PTY) at 21:56 and arrives in Santa Cruz (VVI) at 04:04.
  • What are the most popular airlines that fly from Panama City (PTY) to Santa Cruz (SRZ)?

    Airlines with flights from Panama City (PTY) to Santa Cruz (SRZ): Copa Airlines and United Airlines.
  • What's the most popular airline for direct flights from Panama City (PTY) to Santa Cruz (SRZ)?

    Copa Airlines operates 1 direct flights from Panama City (PTY) to Santa Cruz (SRZ).
  • How many airports in Santa Cruz?

    There are 2 airports near Santa Cruz: El Trompillo Airport and Viru Viru International Airport.

How to find a cheap flight from Panama City to Santa Cruz

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Panama City to Santa Cruz. Book your flights at the right time and save more.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com
Flight Information from Panama City to Santa Cruz

Cheapest direct flight price

S$ 211

Cheapest return ticket price

S$ 581

Cheapest month

March

Peak season for travel

October

Flight distance

3,476.98km

Average flight time

5 hours

Popular airline

Avianca