Cheap Flights from Panama City to Chicago from S$ 422

Frequently Asked Questions

• Which airlines offer the cheapest flights from Panama City to Chicago?

  Based on Trip.com data, Delta Air Lines offers Cheapest nonstop one-way flights from S$ 422 (for example, PTY–MDW on Thu, Nov 5). For a Cheapest nonstop return flight, avianca offers fares from S$ 561, departing on Sun, Nov 1 and returning on Wed, Nov 4.

• Which airlines offer flights from Panama City to Chicago?

  At the moment, several airlines serve connecting flights from Panama City to Chicago, including: United Airlines Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.

• How long is a flight from Panama City (PTY) to Chicago (CHI)?

  It takes about 5 hours 39 minutes to fly from Panama City (PTY) to Chicago (CHI).

• When is the best time to book flights from Panama City to Chicago?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Panama City to Chicago is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How many flights are there from Panama City to Chicago each week?

  On average, 22 direct flights operate each week between Panama City and Chicago. See below the schedules of the main airlines serving this route:
  United Airlines: S/-/T/-/T/F/S – UA7171 (departure at 10:52) United Airlines: S/M/T/W/T/F/S – UA7083 (departure at 03:00)

• How can I find the best deals on flights from Panama City to Chicago?

  Here are some tips for finding the best flight deals from Panama City to Chicago on Trip.com:
  · Be flexible with your travel dates. The cheapest flight is currently on Thu, Nov 5, with one-way fares from just S$ 422.
  · Compare airlines. Copa Airlines currently offers the lowest fares on this route.
  · Set up a price alert to track fare changes without searching every day.
  · Check Trip.com regularly for flight deals and available promo codes.
  · Avoid peak season or book early. January is generally the busiest month for travel to Chicago.
  · Get exclusive promo codes on the Trip.com app.

• When is the best time to book a flight from Panama City to Chicago to get the best price?

  The cheapest month to book a flight from Panama City to Chicago is usually August, when demand is lower.

• Which upcoming date is the cheapest for flights from Panama City to Chicago?

  After crunching the numbers on our October flight calendar, it's currently cheapest to fly from Panama City to Chicago on October 28, 2026 with Copa Airlines, with prices starting at S$ 507.

• Which airports should you choose for flights from Panama City to Chicago?

  Flights to Chicago can arrive at: O'Hare International Airport (ORD), Chicago Midway International Airport (MDW) and Chicago Rockford International Airport (RFD). The most common route connects Tocumen International Airport and O'Hare International Airport (PTY–ORD).

• What is the time difference between Panama City and Chicago?

  The time difference between Chicago and Panama City is 1h.

• How can I change or cancel my flight ticket from Panama City to Chicago?

  Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

• What is the average cost of a one-way flight from Panama City to Chicago?

  Based on Trip.com data for flights departing in the next 30 days, the average one-way fare from Panama City to Chicago is S$ 883. Fares vary by travel date, airline and availability.

• What is the average cost of a round-trip flight from Panama City to Chicago?

  Based on Trip.com data for travel in the next 30 days, the average round-trip fare from Panama City to Chicago is S$ 1,133. The final price depends on the outbound and return dates, airline and fare conditions.

• How do I book flights from Panama City to Chicago on Trip.com?

  Enter Panama City and Chicago, choose your travel dates and passengers, then compare flights by price, duration and baggage. Select a fare, review the change and cancellation rules, enter traveller details and complete payment to receive your confirmation.