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Cheap Flights from Des Moines to Chicago starting at S$ 125

Book one-way or return flights from Des Moines to Chicago from as little as S$ 125. Choose from the popular airlines below and book your flight today!

  • One way
  • Round-trip

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Cheapest time to fly from Des Moines to Chicago

We monitor flight fares to help you find the best deals effortlessly

Displayed prices are calculated based on the lowest average weekly prices of the corresponding route on Trip.com.
Cheapest Airlines flying from Des Moines to Chicago

Compare prices, find the option that best suits your travel needs, and enjoy a comfortable journey with a trusted airline.

Delta Air Lines
From S$ 125
Southwest Airlines
From S$ 149
Frontier Airlines
From S$ 152
United Airlines
From S$ 156
American Airlines
From S$ 169
ANA airlines

Find more flights and airlines

Alternative Routes from Des Moines to Chicago

Searching for potential routes that might be cheaper and faster? Check out these alternative flights from Des Moines to Chicago.

  • Cheapest
    Delta Air Lines
    DSM
    12:06
    6h 29m
    1 transfer
    ORD
    18:35
    Des Moines International Airport - O'Hare International Airport
    Tue, Apr 30Delta Air Lines
    S$ 125
  • Delta Air Lines
    DSM
    12:06
    4h 18m
    1 transfer
    MDW
    16:24
    Des Moines International Airport - Midway International Airport
    Tue, Apr 30Delta Air Lines
    S$ 125
  • Delta Air Lines
    DSM
    12:06
    4h 18m
    1 transfer
    MDW
    16:24
    Des Moines International Airport - Midway International Airport
    Tue, Apr 30Delta Air Lines
    S$ 125
    Find More Flights

Frequently Asked Questions

  • When to buy flight tickets from Des Moines (DSM) to Chicago (CHI) the cheapest?

    Airlines adjust prices for flights from Des Moines to Chicago based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays.
  • How much is a flight from Des Moines (DSM) to Chicago (CHI) cost?

    According to Trip.com's data, the lowest price is around S$ 432.
  • How long is a flight from Des Moines (DSM) to Chicago (CHI)?

    It takes about 1 hour 28 minutes to fly from Des Moines (DSM) to Chicago (CHI).
  • What is the transportation method from the main airport to downtown in Chicago?

    • The distance from O'Hare International Airport to downtown is about 25km, by taxi about 40 minutes.
    • The distance from Midway International Airport to downtown is about 14km, by taxi about 30 minutes.
  • What time does the earliest flight from Des Moines to Chicago depart?

    The earliest flight departs from Des Moines (DSM) at 06:00 and arrives in Chicago (ORD) at 07:19.
  • What time does the latest flight from Des Moines to Chicago depart?

    The latest flight departs from Des Moines (DSM) at 18:45 and arrives in Chicago (ORD) at 20:11.
  • What are the most popular airlines that fly from Des Moines (DSM) to Chicago (CHI)?

    Airlines with flights from Des Moines (DSM) to Chicago (CHI): Aer Lingus, Alaska Airlines, United Airlines, British Airways, Ana, Copa Airlines, Qatar Airways, American Airlines, IBERIA and Lufthansa.
  • What's the most popular airline for direct flights from Des Moines (DSM) to Chicago (CHI)?

    American Airlines operates 1 direct flights from Des Moines (DSM) to Chicago (CHI).
  • How many airports in Chicago?

Find cheapest flight ticket from Des Moines to Chicago

Cheapest direct flight price

S$ 124

Cheapest return ticket price

S$ 275

Cheapest month

December

Peak season for travel

September