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Cheap Flights from Des Moines to Cape Girardeau

We've found these cheap flights for you. You can book one-way or return flight tickets.

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Flying from Des Moines to Cape Girardeau

The distance between Des Moines and Cape Girardeau is approximately 593.93km. Based on Trip.com's data, travel demand peaks in December. The off-season for travel is February.

Cheapest return ticket priceS$ 777
Off-season for travelFebruary
Peak season for travelDecember
Flight distance593.93km

Cheapest time to fly from Des Moines to Cape Girardeau

The cheapest time for Des Moines to Cape Girardeau flights: Dec 21 to Dec 28 — one way flight prices from S$ 777.

Cheapest flights
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  • 714
  • 1421
  • 2128
  • Jan

    284
  • 411
  • 1118
  • 1825
  • Feb

    251
  • 18
  • 815
  • 1522
  • Mar

    221
Displayed prices are calculated based on the lowest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When is the best time to book flights from Des Moines to Cape Girardeau?

    By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Des Moines to Cape Girardeau is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • To find best deals on flights from Des Moines to Cape Girardeau, you can use various tools on Trip.com:
    · Set up price alerts to easily monitor ticket prices without having to check every day.
    · Check Trip.com flight deals and promo codes frequently.
    · Avoid peak season unless you book very early. It seems the peak season for Cape Girardeau travel is around December.
    · Get exclusive promo codes for Trip.com app users.
  • The cheapest months to fly from Des Moines to Cape Girardeau is February, when demand for travel is lower.
  • After crunching the numbers on our December flight calendar, it's currently cheapest to fly from Des Moines to Cape Girardeau on December 27, 2025 with United Airlines, with prices starting at S$ 776.
  • The time difference between Cape Girardeau and Des Moines is 0h.
  • Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.