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Myrtle Beach International Airport to Des Moines International Airport flight
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Cheap Flights from Myrtle Beach International Airport to Des Moines International Airport

Search for flights from Myrtle Beach to Des Moines and check out affordable one-way and round-trip options.

  • One way
  • Round-trip
sortSort: Price (Lowest)
  • Sort: Price (Lowest)
  • Sort: Departure (Earliest)
      • MYR20:59
        22h 33m
        1 stop
        DSM18:32
        Myrtle Beach - Des Moines|Sat, Jun 29|Spirit Airlines
        S$ 205S$ 502
        59% OFF
        59% OFF
        S$ 502S$ 205
      • MYR19:46
        4h 17m
        1 stop
        DSM23:03
        Myrtle Beach - Des Moines|Tue, Aug 20|American Airlines
        S$ 216S$ 502
        56% OFF
        56% OFF
        S$ 502S$ 216
      • MYR13:05
        7h 23m
        1 stop
        DSM19:28
        Myrtle Beach - Des Moines|Wed, Jun 26|Delta Air Lines
        S$ 338S$ 502
        33% OFF
        33% OFF
        S$ 502S$ 338
      • MYR19:03
        4h 21m
        1 stop
        DSM22:24
        Myrtle Beach - Des Moines|Tue, Aug 20|Delta Air Lines
        S$ 361
        S$ 361
      • MYR20:09
        5h 15m
        1 stop
        DSM00:24
        Myrtle Beach - Des Moines|Sun, Jul 7|American Airlines
        S$ 378
        S$ 378
      • MYR13:30
        5h 19m
        1 stop
        DSM17:49
        Myrtle Beach - Des Moines|Wed, Jun 26|United Airlines
        S$ 380
        S$ 380
      • MYR11:22
        4h 55m
        1 stop
        DSM15:17
        Myrtle Beach - Des Moines|Wed, Jun 26|American Airlines
        S$ 396
        S$ 396
      • MYR18:25
        6h 40m
        1 stop
        DSM00:05
        Myrtle Beach - Des Moines|Sat, Jun 29|American Airlines
        S$ 400
        S$ 400
      • MYR15:20
        7h 26m
        1 stop
        DSM21:46
        Myrtle Beach - Des Moines|Sat, Jun 29|United Airlines
        S$ 406
        S$ 406
      • MYR13:30
        9h 14m
        1 stop
        DSM21:44
        Myrtle Beach - Des Moines|Tue, Jun 25|United Airlines
        S$ 428
        S$ 428
      • MYR13:00
        3h 5m
        Direct
        DSM14:00
        Myrtle Beach - Des Moines|Mon, Jul 1|Spirit Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Selected Airlines from Myrtle Beach International Airport to Des Moines International Airport

See which airlines fly from Myrtle Beach to Des Moines. Find the airline that best meets your travel needs by comparing prices and treat yourself to an enjoyable journey.

Spirit Airlines
From S$ 205
American Airlines
From S$ 216
Delta Air Lines
From S$ 338
United Airlines
From S$ 345
Frontier Airlines
From S$ 358
Sun Country Airlines
From S$ 480
Allegiant Air
From S$ 853
ANA airlines

Find more flights and airlines

Flight Schedule from Myrtle Beach International Airport to Des Moines International Airport

Check the schedule for flights from Myrtle Beach to Des Moines and find the flight that best matches your travel plans.

Flight info.
Departure
Arrival
Weekly Schedule

  1. DL3162

    Delta Air Lines

    06:00

    MYR

    1.3h

    07:19

    ATL

    SMTWTFS
    Search

  2. DL1704

    Delta Air Lines

    09:06

    ATL

    2.1h

    10:15

    DSM

    SMTWTFS

  3. AA5674

    American Airlines

    10:30

    MYR

    1.5h

    11:59

    DCA

    SMTWT-S
    Search

  4. AA4435

    American Airlines

    13:40

    DCA

    2.6h

    15:19

    DSM

    SMTWTFS

  5. AA2529

    American Airlines

    11:22

    MYR

    1.1h

    12:30

    CLT

    SMTWT-S
    Search

  6. AA2962

    American Airlines

    13:32

    CLT

    2.4h

    14:58

    DSM

    SMTWTFS

  7. AA5347

    American Airlines

    11:29

    MYR

    1.2h

    12:43

    CLT

    -----F-
    Search

  8. AA2962

    American Airlines

    13:32

    CLT

    2.4h

    14:58

    DSM

    SMTWTFS

  9. UA2278

    United Airlines

    13:10

    MYR

    2.4h

    14:34

    ORD

    SMTWT-S
    Search

  10. UA5283

    United Airlines

    16:20

    ORD

    1.5h

    17:49

    DSM

    SMT----

  11. DL3182

    Delta Air Lines

    14:23

    MYR

    1.4h

    15:45

    ATL

    SMTWTFS
    Search

  12. DL2086

    Delta Air Lines

    16:37

    ATL

    2.2h

    17:48

    DSM

    SMTWTFS

  13. AA2180

    American Airlines

    17:52

    MYR

    3.0h

    19:54

    DFW

    SMTWTFS
    Search

  14. AA1371

    American Airlines

    21:19

    DFW

    1.9h

    23:14

    DSM

    SMTWTFS

  15. AA5465

    American Airlines

    18:12

    MYR

    1.2h

    19:24

    CLT

    SMTWTFS
    Search

  16. AA1325

    American Airlines

    20:45

    CLT

    2.5h

    22:13

    DSM

    SMTWTFS

  17. DL3170

    Delta Air Lines

    18:57

    MYR

    1.4h

    20:20

    ATL

    SMTWTFS
    Search

  18. DL2306

    Delta Air Lines

    21:10

    ATL

    2.1h

    22:19

    DSM

    SMTWTFS

  19. AA1861

    American Airlines

    19:55

    MYR

    1.1h

    21:00

    CLT

    SMTWTFS
    Search

  20. AA1325

    American Airlines

    20:45

    CLT

    2.5h

    22:13

    DSM

    SMTWTFS
Find more flights and airlines

Myrtle Beach International Airport to Des Moines International Airport Flights Info

Flight distance1,561.76km
Cheapest one-way ticket priceS$ 204

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