Cheap Flights from St. Louis to Panama City starting at S$ 151

We've found these cheap flights for you. You can book one-way or return flight tickets.

Round-trip
One way

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Cheapest time to fly from St. Louis to Panama City

We monitor flight fares to help you find the best deals effortlessly

Cheapest flights

From price

Apr

30 6
6 13
13 20
20 27
May

27 4
4 11
11 18
18 25
Jun

25 1
1 8
8 15
15 22

Displayed prices are calculated based on the lowest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

When to buy flight tickets from St. Louis (STL) to Panama City (ECP) the cheapest?

Airlines adjust prices for flights from St. Louis to Panama City based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the cheapest flight prices on Tuesdays, Wednesdays, and Saturdays.
How much is a flight from St. Louis (STL) to Panama City (ECP) cost?

According to Trip.com's data, the lowest price is around S$ 647.
How long is a flight from St. Louis (STL) to Panama City (ECP)?

It takes about 1 hour 47 minutes to fly from St. Louis (STL) to Panama City (ECP).
What are the most popular airlines that fly from St. Louis (STL) to Panama City (ECP)?

Airlines with flights from St. Louis (STL) to Panama City (ECP): Southwest Airlines.
What's the most popular airline for direct flights from St. Louis (STL) to Panama City (ECP)?

Southwest Airlines operates 1 direct flights from St. Louis (STL) to Panama City (ECP).
How many airports in Panama City?

There are 1 airports near Panama City: Northwest Florida Beaches International Airport.

How to find a cheap flight from St. Louis to Panama City

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from St. Louis to Panama City. Book your flights at the right time and save more.

Choose your dates flexibly and get the best deals on flights from St. Louis to Panama City.

Tap 'Date' on the flight search bar to browse the calendar for St. Louis to Panama City airfare over the next 6 months in 2025. If you're looking to fly within the next 3 months, the cheapest date seems to be Tue, Apr 22, with one-way flights starting at S$ 151.

Compare cheap flight deals from hundreds of airlines for St. Louis to Panama City flights.

Our extensive search lets you compare prices from over 500 airlines to find the cheapest flights from St. Louis to Panama City. The cheapest flight at the moment is with Delta Air Lines.

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Book early or wait for last-minute deals.

It's always better to book early. Flight tickets are often at their lowest when first released, usually a year ahead of departure. Keep an eye out as soon as your desired flights open for booking. If you miss the early deals, you may still find lower prices closer to your travel date.

Search for flights on the go.

For the best flight booking experience on the go, download Trip.com and search for cheap flights from St. Louis to Panama City to get your exclusive deals.

Find cheapest flight ticket from St. Louis to Panama City

Cheapest one-way flight price	S$ 150
Off-season for travel	March
Peak season for travel	January
Flight distance	1,025.63km
Average flight time	1 hour 47 minutes
Popular airline	Delta Air Lines