Trip.com
>
Flights
>
Czech Republic
>
Flights to Prague
Hotels in Prague
>
Cheap Flights from Santo Domingo to Prague

Popular airlines from Santo Domingo to Prague

Choose from 1 carriers that fly from Santo Domingo to Prague, including Smartwings, Enjoy the cheapest tickets on this route with IBERIA.
Smartwings logo Smartwings

Find the cheapest flights from Santo Domingo to Prague within the next three months. Book one-way flights from S$ 446 or return tickets from S$ 2,128.

      • SDQ 21:45
        12h 10m
        1 stop
        PRG 14:55
        Santo Domingo - Prague | Sun, Nov 16 | IBERIA
        PRG 15:40
        33h 30m
        1 stop
        SDQ 20:10
        Prague - Santo Domingo | Thu, Nov 20 | IBERIA
        S$ 2,128 S$ 3,748
        43% OFF
        43% OFF
        S$ 3,748 S$ 2,128
      • SDQ 17:55
        20h
        1 stop
        PRG 18:55
        Santo Domingo - Prague | Mon, Dec 1 | IBERIA
        PRG 20:00
        25h 15m
        1 stop
        SDQ 16:15
        Prague - Santo Domingo | Thu, Dec 4 | IBERIA
        S$ 2,191 S$ 3,748
        42% OFF
        42% OFF
        S$ 3,748 S$ 2,191
      • SDQ 22:50
        13h
        1 stop
        PRG 16:50
        Santo Domingo - Prague | Wed, Nov 19 | Air Europa
        PRG 09:55
        15h 20m
        1 stop
        SDQ 20:15
        Prague - Santo Domingo | Sun, Nov 23 | Air Europa
        S$ 2,243 S$ 3,748
        40% OFF
        40% OFF
        S$ 3,748 S$ 2,243
      • SDQ 22:50
        13h
        1 stop
        PRG 16:50
        Santo Domingo - Prague | Sun, Nov 16 | Air Europa
        PRG 09:55
        15h 20m
        1 stop
        SDQ 20:15
        Prague - Santo Domingo | Thu, Nov 20 | Air Europa
        S$ 2,361
        37% OFF
        S$ 3,748 S$ 2,361
      • SDQ 21:45
        12h 10m
        1 stop
        PRG 14:55
        Santo Domingo - Prague | Wed, Nov 19 | IBERIA
        PRG 12:30
        32h 45m
        1 stop
        SDQ 16:15
        Prague - Santo Domingo | Sun, Nov 23 | IBERIA
        S$ 2,485
        34% OFF
        S$ 3,748 S$ 2,485
      • SDQ 22:50
        13h
        1 stop
        PRG 16:50
        Santo Domingo - Prague | Tue, Dec 2 | Air Europa
        PRG 16:55
        30h 20m
        1 stop
        SDQ 18:15
        Prague - Santo Domingo | Tue, Dec 9 | Condor Airlines
        S$ 2,519
        33% OFF
        S$ 3,748 S$ 2,519
      • SDQ 17:55
        16h
        1 stop
        PRG 14:55
        Santo Domingo - Prague | Tue, Dec 2 | IBERIA
        PRG 16:55
        30h 20m
        1 stop
        SDQ 18:15
        Prague - Santo Domingo | Tue, Dec 9 | Condor Airlines
        S$ 2,721
        27% OFF
        S$ 3,748 S$ 2,721
      • SDQ 17:55
        17h 55m
        1 stop
        PRG 16:50
        Santo Domingo - Prague | Sat, Dec 13 | IBERIA
        PRG 16:55
        30h
        1 stop
        SDQ 17:55
        Prague - Santo Domingo | Sat, Dec 20 | Condor Airlines
        S$ 3,126
        17% OFF
        S$ 3,748 S$ 3,126
      • SDQ 22:50
        15h 5m
        1 stop
        PRG 18:55
        Santo Domingo - Prague | Sat, Dec 13 | Air Europa
        PRG 16:55
        30h
        1 stop
        SDQ 17:55
        Prague - Santo Domingo | Sat, Dec 20 | Condor Airlines
        S$ 3,186
        15% OFF
        S$ 3,748 S$ 3,186
      • SDQ 13:00
        17h 25m
        1 stop
        PRG Invalid Date
        Santo Domingo - Prague | Tue, Nov 18 | Normal Airline
        PRG 15:00
        6h
        Direct
        SDQ 16:00
        Prague - Santo Domingo | Thu, Nov 20 | Normal Airline
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Flying from Santo Domingo to Prague

The distance between Santo Domingo and Prague is about 8,033.54km. The most popular month to Prague is August. The off-season for travel is October.

Cheapest one-way flight priceS$ 446
Cheapest return ticket priceS$ 2,128
Off-season for travelOctober
Peak season for travelAugust
Flight distance8,033.54km
Popular airlineSmartwings

Cheapest time to fly from Santo Domingo to Prague

The cheapest time for Santo Domingo to Prague flights: Dec 21 to Dec 28 — one way flight prices from S$ 445.

Cheapest flights
From price
Search
  • 1623
  • 2330

  • Dec

    307
  • 714
  • 1421
  • 2128

  • Jan

    284
  • 411
  • 1118
  • 1825

  • Feb

    251
  • 18
Displayed prices are calculated based on the lowest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When is the best time to book flights from Santo Domingo to Prague?

    By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Santo Domingo to Prague is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • The cheapest months to fly from Santo Domingo to Prague is October, when demand for travel is lower.
  • After crunching the numbers on our November flight calendar, it's currently cheapest to fly from Santo Domingo to Prague on November 16, 2025 with IBERIA, with prices starting at S$ 2,127.
  • The time difference between Prague and Santo Domingo is 5h.
  • Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

Find Cheap Flights & Deals on Trip.com