Cheap Flights from San Francisco to Guayaquil from S$ 294

Frequently Asked Questions

• Which airlines offer the cheapest flights from San Francisco to Guayaquil?

  Based on Trip.com data, Jetblue Airways offers Cheapest nonstop one-way flights from S$ 294 (for example, SFO–GYE on Sun, Sep 6). For a Cheapest nonstop return flight, Copa Airlines offers fares from S$ 916, departing on Sat, Oct 31 and returning on Sat, Nov 7.

• Which airlines offer flights from San Francisco to Guayaquil?

  At the moment, several airlines serve connecting flights from San Francisco to Guayaquil, including: Copa Airlines Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.

• When is the best time to book flights from San Francisco to Guayaquil?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from San Francisco to Guayaquil is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How can I find the best deals on flights from San Francisco to Guayaquil?

  Here are some tips for finding the best flight deals from San Francisco to Guayaquil on Trip.com:
  · Be flexible with your travel dates. The cheapest flight is currently on Sun, Sep 6, with one-way fares from just S$ 294.
  · Compare airlines. Jetblue Airways currently offers the lowest fares on this route.
  · Set up a price alert to track fare changes without searching every day.
  · Check Trip.com regularly for flight deals and available promo codes.
  · Avoid peak season or book early. July is generally the busiest month for travel to Guayaquil.
  · Get exclusive promo codes on the Trip.com app.

• When is the best time to book a flight from San Francisco to Guayaquil to get the best price?

  The cheapest month to book a flight from San Francisco to Guayaquil is usually October, when demand is lower.

• Which upcoming date is the cheapest for flights from San Francisco to Guayaquil?

  After crunching the numbers on our September flight calendar, it's currently cheapest to fly from San Francisco to Guayaquil on September 6, 2026 with Jetblue Airways, with prices starting at S$ 294.

• Which airports should you choose for flights from San Francisco to Guayaquil?

  Flights to Guayaquil can arrive at: José Joaquín de Olmedo International Airport (GYE). The most common route connects San Francisco International Airport and José Joaquín de Olmedo International Airport (SFO–GYE).

• What is the time difference between San Francisco and Guayaquil?

  The time difference between Guayaquil and San Francisco is 3h.

• How can I change or cancel my flight ticket from San Francisco to Guayaquil?

  Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

• What is the average cost of a one-way flight from San Francisco to Guayaquil?

  Based on Trip.com data for flights departing in the next 30 days, the average one-way fare from San Francisco to Guayaquil is S$ 944. Fares vary by travel date, airline and availability.

• How do I book flights from San Francisco to Guayaquil on Trip.com?

  Enter San Francisco and Guayaquil, choose your travel dates and passengers, then compare flights by price, duration and baggage. Select a fare, review the change and cancellation rules, enter traveller details and complete payment to receive your confirmation.