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Cheap Flights from Panama City to Sao Paulo

Popular airlines from Panama City to Sao Paulo

Choose from 1 carriers that fly from Panama City to Sao Paulo, including avianca, Enjoy the cheapest tickets on this route with Copa Airlines.

Find direct flights from Panama City to Sao Paulo within the next three months. Book one-way flights from S$ 1,081 or return tickets from S$ 660.

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Flying from Panama City to Sao Paulo

The distance between Panama City and Sao Paulo is about 5,084.63km. It takes around 7 hours on average to fly from Panama City to Sao Paulo. The most popular month to Sao Paulo is July. The off-season for travel is September.

Cheapest one-way flight priceS$ 254
Cheapest return ticket priceS$ 595
Off-season for travelSeptember
Peak season for travelJuly
Flight distance5,084.63km
Average flight time7 hours
Popular airlineavianca

Cheapest time to fly from Panama City to Sao Paulo

The cheapest time for Panama City to Sao Paulo flights: Nov 30 to Dec 7 — one way flight prices from S$ 286.

Cheapest flights
From price
Search
  • 1623
  • 2330
  • Dec

    307
  • 714
  • 1421
  • 2128
  • Jan

    284
  • 411
  • 1118
  • 1825
  • Feb

    251
  • 18
Displayed prices are calculated based on the lowest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • Which airlines offer flights from Panama City to Sao Paulo?

    At the moment, several airlines serve connecting flights from Panama City to Sao Paulo, including: avianca Selected airlines are based on historical data collected from flight bookings made by users on Trip.com within the last 90 days.
  • It takes about 7 hours to fly from Panama City (PTY) to Sao Paulo (SAO).
  • By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Panama City to Sao Paulo is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.
  • The cheapest months to fly from Panama City to Sao Paulo is September, when demand for travel is lower.
  • After crunching the numbers on our November flight calendar, it's currently cheapest to fly from Panama City to Sao Paulo on November 17, 2025 with Copa Airlines, with prices starting at S$ 245.
  • You can land at any one of the following hubs in Sao Paulo, with Tocumen International Airport to São Paulo/Guarulhos International Airport (PTY-GRU) is by far the most common option on this route: São Paulo–Congonhas Airport (CGH) São Paulo/Guarulhos International Airport (GRU) Viracopos International Airport (VCP).
  • The time difference between Sao Paulo and Panama City is 2h.
  • Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.