Cheap Flights from Panama City to Medellin from S$ 177

Frequently Asked Questions

• Which airlines offer the cheapest flights from Panama City to Medellin?

  Based on Trip.com data, Copa Airlines offers Cheapest nonstop one-way flights from S$ 177 (for example, PTY–MDE on Tue, Nov 3). For a Cheapest nonstop return flight, avianca offers fares from S$ 333, departing on Sat, Sep 12 and returning on Wed, Sep 16.

• Which airlines offer direct flights from Panama City to Medellin?

  At the moment, you can catch a direct flight from Panama City to Medellin with the following airlines, including: Copa Airlines Selected airlines are based on historical data collected from flight bookings users made on Trip.com within the last 90 days.

• How long is a flight from Panama City (PTY) to Medellin (MDE)?

  It takes about 1 hour 24 minutes to fly from Panama City (PTY) to Medellin (MDE).

• When is the best time to book flights from Panama City to Medellin?

  By analyzing data from all airlines on the Trip.com flight calendar, it looks like the best time to book a flight from Panama City to Medellin is around 40 days (6 weeks) in advance, and the best time to fly is usually on Tuesday, Wednesday, and Saturday. Tuesday typically offers the cheapest flights for departure, while Saturday offers the best return deals.

• How many flights are there from Panama City to Medellin each week?

  On average, 49 direct flights operate each week between Panama City and Medellin. See below the schedules of the main airlines serving this route:
  Copa Airlines: S/M/T/W/T/F/S – CM150 (departure at 07:07) Copa Airlines: S/M/T/W/T/F/S – CM397 (departure at 09:59)

• How can I find the best deals on flights from Panama City to Medellin?

  Here are some tips for finding the best flight deals from Panama City to Medellin on Trip.com:
  · Be flexible with your travel dates. The cheapest flight is currently on Tue, Nov 3, with one-way fares from just S$ 177.
  · Compare airlines. Copa Airlines currently offers the lowest fares on this route.
  · Set up a price alert to track fare changes without searching every day.
  · Check Trip.com regularly for flight deals and available promo codes.
  · Avoid peak season or book early. September is generally the busiest month for travel to Medellin.
  · Get exclusive promo codes on the Trip.com app.

• When is the best time to book a flight from Panama City to Medellin to get the best price?

  The cheapest month to book a flight from Panama City to Medellin is usually November, when demand is lower.

• Which upcoming date is the cheapest for flights from Panama City to Medellin?

  After crunching the numbers on our September flight calendar, it's currently cheapest to fly from Panama City to Medellin on September 12, 2026 with Copa Airlines, with prices starting at S$ 174.

• Which airports should you choose for flights from Panama City to Medellin?

  Flights to Medellin can arrive at: Olaya Herrera Airport (EOH)Jose Maria Cordova International Airport (MDE). The most common route connects Tocumen International Airport and Jose Maria Cordova International Airport (PTY–MDE).

• What is the time difference between Panama City and Medellin?

  The time difference between Medellin and Panama City is 0m.

• How can I change or cancel my flight ticket from Panama City to Medellin?

  Tickets can only be changed or cancelled if permitted by airline policy. To submit a change or cancellation request, go to the flight bookings page, select the option to change or cancel your booking, choose the relevant passengers and segment, and submit a request. Please note that additional charges may apply according to the airline ticket policy. However, if the flight has been rescheduled and you would like to change or cancel your ticket, you can submit an involuntary cancellation request. For more details about change and cancellation policies, please check the customer support pages.

• What is the average cost of a one-way flight from Panama City to Medellin?

  Based on Trip.com data for flights departing in the next 30 days, the average one-way fare from Panama City to Medellin is S$ 685. Fares vary by travel date, airline and availability.

• What is the average cost of a round-trip flight from Panama City to Medellin?

  Based on Trip.com data for travel in the next 30 days, the average round-trip fare from Panama City to Medellin is S$ 429. The final price depends on the outbound and return dates, airline and fare conditions.

• How do I book flights from Panama City to Medellin on Trip.com?

  Enter Panama City and Medellin, choose your travel dates and passengers, then compare flights by price, duration and baggage. Select a fare, review the change and cancellation rules, enter traveller details and complete payment to receive your confirmation.