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2026 cruises departing from Rome – Best cruise deals and departure dates

Explore the best cruises departing from Rome in Rome, including short trips and luxury voyages. Compare cruise companies, itineraries, and prices on Trip.com to find your ideal cruise departing from undefined.

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8-day · Rome - Santorini - Kusadasi - Mykonos - Naples - Rome
Odyssey of the Seas

8-day · Rome - Santorini - Kusadasi - Mykonos - Naples - Rome

Royal Caribbean InternationalOdyssey of the Seas
5.0(2)
Royal Caribbean International · RCI
3 May 2026
Rome
From € 594
12-day · Rome - Greece - Türkiye - Italy - Rome
Celebrity Ascent
-34%

12-day · Rome - Greece - Türkiye - Italy - Rome

Celebrity CruisesCelebrity Ascent
2.5(1)
Celebrity Cruises · Celebrity Cruises
15 June 2026
Rome
€ 2,066
From € 1,358
8-day · Rome - Genoa - Marseille - Tarragona - Valencia - Florence - Rome
MSC Orchestra

8-day · Rome - Genoa - Marseille - Tarragona - Valencia - Florence - Rome

MSC CruisesMSC Orchestra
4.4(12)
MSC Cruises · MSC
5 May 2026
Rome
From € 586
8-day · Rome - Savona - Marseille - Barcelona - La Goulette - Palermo - Rome
Costa Smeralda

8-day · Rome - Savona - Marseille - Barcelona - La Goulette - Palermo - Rome

Costa CruisesCosta Smeralda
4.1(15)
Costa Cruises · Costa
17 April 2026
Rome
From € 691
8-day · Rome - Mykonos - Kusadasi - Marmaris - Naples - Rome
MSC Divina

8-day · Rome - Mykonos - Kusadasi - Marmaris - Naples - Rome

MSC CruisesMSC Divina
4.5(29)
MSC Cruises · MSC
1 May 2026
Rome
From € 438
8-day · Rome - Valencia - Barcelona - Marseille - Genoa - Florence - Rome
MSC Orchestra

8-day · Rome - Valencia - Barcelona - Marseille - Genoa - Florence - Rome

MSC CruisesMSC Orchestra
4.4(12)
MSC Cruises · MSC
16 April 2026
Rome
From € 812
8-day · Rome - Marseille - Barcelona - Palma de Mallorca - La Spezia - Rome
Legend of the Seas
-25%

8-day · Rome - Marseille - Barcelona - Palma de Mallorca - La Spezia - Rome

Royal Caribbean InternationalLegend of the Seas
Royal Caribbean International · RCI
4 July 2026
Rome
€ 1,817
From € 1,364
Eligible bookings will receive a discount of up to 60% off on second passenger's cruise fare. 30% discount applies to guests 3 and 4*. Taxes, fees and port expense are additional and applicable to all guests.
8-day · Rome - Messina - Valletta - Barcelona - Marseille - Genoa - Naples
MSC World Europa

8-day · Rome - Messina - Valletta - Barcelona - Marseille - Genoa - Naples

MSC CruisesMSC World Europa
4.6(69)
MSC Cruises · MSC
13 April 2026
Rome
From € 1,238
4-day · Rome - Mykonos - Kusadasi
MSC Divina

4-day · Rome - Mykonos - Kusadasi

MSC CruisesMSC Divina
4.5(29)
MSC Cruises · MSC
24 April 2026
Rome
From € 257
10-day · Rome - Greece - Türkiye - Italy - Rome
Odyssey of the Seas

10-day · Rome - Greece - Türkiye - Italy - Rome

Royal Caribbean InternationalOdyssey of the Seas
5.0(2)
Royal Caribbean International · RCI
24 April 2026
Rome
From € 884
8-day · Rome - Palermo - Ibiza - Barcelona - Marseille - Genoa - Rome
MSC Seaview

8-day · Rome - Palermo - Ibiza - Barcelona - Marseille - Genoa - Rome

MSC CruisesMSC Seaview
4.6(20)
MSC Cruises · MSC
24 May 2026
Rome
From € 803
8-day · Rome - Genoa - Marseille - Valencia - Ibiza - Cagliari - Rome
MSC Musica

8-day · Rome - Genoa - Marseille - Valencia - Ibiza - Cagliari - Rome

MSC CruisesMSC Musica
4.3(32)
MSC Cruises · MSC
18 May 2026
Rome
From € 699
9-day · Rome - Naples - Barcelona - Valletta - Corfu (Corfu) - Bari
MSC Fantasia

9-day · Rome - Naples - Barcelona - Valletta - Corfu (Corfu) - Bari

MSC CruisesMSC Fantasia
4.5(50)
MSC Cruises · MSC
24 April 2026
Rome
From € 561
4-day · Rome - Naples - Barcelona
MSC Fantasia

4-day · Rome - Naples - Barcelona

MSC CruisesMSC Fantasia
4.5(50)
MSC Cruises · MSC
24 April 2026
Rome
From € 400
10-day · Rome - Naples - La Spezia - Portofino - Nice - Marseille - Barcelona
Celebrity Equinox
-38%

10-day · Rome - Naples - La Spezia - Portofino - Nice - Marseille - Barcelona

Celebrity CruisesCelebrity Equinox
4.7(4)
Celebrity Cruises · Celebrity Cruises
5 May 2026
Rome
€ 2,200
From € 1,364
7-day · Rome - Mykonos - Kusadasi - Marmaris - Naples
MSC Divina

7-day · Rome - Mykonos - Kusadasi - Marmaris - Naples

MSC CruisesMSC Divina
4.5(29)
MSC Cruises · MSC
24 April 2026
Rome
From € 479
8-day · Rome - Genoa - Marseille - Barcelona - Cagliari - Naples - Rome
Costa Toscana

8-day · Rome - Genoa - Marseille - Barcelona - Cagliari - Naples - Rome

Costa CruisesCosta Toscana
3.4(5)
Costa Cruises · Costa
16 April 2026
Rome
From € 813
8-day · Rome - Palma de Mallorca - Barcelona - Cannes - Genoa - La Spezia - Rome
MSC Grandiosa

8-day · Rome - Palma de Mallorca - Barcelona - Cannes - Genoa - La Spezia - Rome

MSC CruisesMSC Grandiosa
4.5(15)
MSC Cruises · MSC
13 May 2026
Rome
From € 681
8-day · Rome - Savona - Marseille - Palma de Mallorca - Valencia - La Spezia - Rome
Costa Pacifica

8-day · Rome - Savona - Marseille - Palma de Mallorca - Valencia - La Spezia - Rome

Costa CruisesCosta Pacifica
4.2(13)
Costa Cruises · Costa
2 May 2026
Rome
From € 597
6-day · Rome - Valencia - Florence - Rome
MSC Orchestra

6-day · Rome - Valencia - Florence - Rome

MSC CruisesMSC Orchestra
4.4(12)
MSC Cruises · MSC
23 April 2026
Rome
From € 443